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filingDate 2003-10-24^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2008-07-15^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79489466eca81d8ec119c62168a3fa06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_318cafdfefb46f2b3b3e3db968fbb431
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publicationDate 2008-07-15^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-7399764-B2
titleOfInvention Inhibitors of Akt activity
abstract The present invention is directed to compounds which contain a five-membered heterocyclic ring fused to a substituted pyrazine moiety which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.
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priorityDate 2002-10-30^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID36897
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID12371
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5468
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID378669
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID482154
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID73950587
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID25402
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID540786
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID21912866
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID157847023
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID56988701
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID39445
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID136619339
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID10224496
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID249022675
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID243239519
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID21912867
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID4829
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID374120
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID12367
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID11104750
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID452501
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419688930
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID161025236
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID69019
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID2370
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID232
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5465
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID107670
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID456798909
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID21103194
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID374100
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6437057
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID418090
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID554230
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID70190
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID281350
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID129662076
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID312145
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID25058199
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID464713
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5493302
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID68669
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID176870
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID235431637
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID472335
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6917
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5329098
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID22198
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID608246

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