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filingDate 2006-01-18^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2009-08-18^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-7575890-B2
titleOfInvention Method for rapid detection and evaluation of cultured cell growth
abstract Provided is a method and system for the rapid and accurate detection of growth and metabolism of a cellular microorganism in a population of microorganisms in a non-liquid, culture medium. Further provided is a gelled culture medium containing a non-toxic, water-soluble, phosphorescent compound which measures oxygen content (partial pressure) of an microorganism also contained therein, by oxygen-dependent quenching of phosphorescence; or the gel contains a fluorescent pH indicator that demonstrates growth of the microorganism by pH-dependent intensity change or wavelength shift in the emission spectrum. Further provided is a system and method for killing undesirable microorganisms or colonies in the culture medium without harming the surrounding microorganisms.
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