| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1224e3c07b7cc5684ee81d9e1e5ee15c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P1-00 |
| filingDate |
2007-09-13^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2009-08-18^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63e24c41c56e854989d3b64a8929d49c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_126e9133867e0fa97dfc9d74ebad248f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8ce467dd8b9d998809bbfd087519fe2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db5911e651b68bcbf831470df0bfed73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f56aae4fddae44cafed1c4b2ddeb3a95
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44124b234999c1ae00131edd4be8ec5e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_448de294fd5687514961ff1bce45c274 |
| publicationDate |
2009-08-18^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7575891-B2 |
| titleOfInvention |
Process for production of diphtheria toxin |
| abstract |
The present invention provides a method of purifying diphtheria toxin comprising (1) fermenting a microorganism strain capable of producing diphtheria toxin using glucose as a carbon source, said method comprising adding glucose to a growing culture whereby the addition of glucose maintains microorganism growth effective to support diphtheria toxin production; and (2) purifying the diphtheria toxin from the culture by contacting a toxin containing preparation derived therefrom with an ion exchange matrix, eluting a fraction containing the toxin, applying the eluate to a hydrophobic matrix, and eluting a fraction containing the toxin. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8906636-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9169304-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9849177-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8530171-B2 |
| priorityDate |
1999-02-26^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |