http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7629355-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_20f9ead623313f8c91c145cd5b4fc776 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 |
| filingDate | 2004-10-14^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-12-08^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b45a0b8a64f94fe6ba526c4125364389 |
| publicationDate | 2009-12-08^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7629355-B2 |
| titleOfInvention | Treatment of chemical dependency with substantially nonaddicting normorphine and norcodeine derivatives |
| abstract | A method is provided for treating a drug-dependent individual so as to effect withdrawal from a drug of abuse, e.g., an opiate such as heroin or oxycodone, a stimulant such as cocaine, or alcohol. The method involves substitution therapy wherein a substantially nonaddicting normorphine or norcodeine derivative is substituted for the drug of abuse. The active agent has the structure of formula (I) n nwherein: R is H, alkyl, or acyl; X is CH(OR′) or C═O, wherein R′ is H or acyl; α is an optional double bond, with the proviso that when α is present, then X is necessarily CH(OH), or an acid addition salt thereof, wherein preferred such agents are in a stereoisomerically pure form that corresponds to that of N-[(1R)-1-cyclopropylethyl]-normorphine (1) which melts at approximately 188° C.-189° C. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11247999-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8987293-B2 |
| priorityDate | 2003-10-14^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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