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filingDate 2007-10-01^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2010-08-31^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec20d7c1c58b46b0c0252ee2f4c85cb2
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publicationDate 2010-08-31^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-7785592-B2
titleOfInvention Stabilized liquid anti-RSV antibody formulations
abstract The present invention provides liquid formulations of SYNAGIS® or an antigen-binding fragment thereof that immunospecifically bind to a respiratory syncytial virus (RSV) antigen, which formulations exhibit stability, low to undetectable levels of aggregation, and very little to no loss of the biological activities of SYNAGIS® or an antigen-binding fragment thereof, even during long periods of storage. In particular, the present invention provides liquid formulations of SYNAGIS® or an antigen-binding fragment thereof which immunospecifically binds to a RSV antigen, which formulations are substantially free of surfactant, inorganic salts, and/or other common excipients. Furthermore, the invention provides method of preventing, treating or ameliorating symptoms associated with RSV infection utilizing liquid formulations of the present invention.
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