abstract |
This invention is directed to drug conjugates of certain ion channel modulating compounds having the following formula: n nwherein A, X, R 1 , R 2 , R 3 , R 4 , R 5 , LB, L and DM are defined herein, including isolated enantiomeric and diastereomeric isomers thereof, and mixtures thereof. Pharmaceutical compositions and methods of use are also disclosed. |