http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7893273-B2

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34fb9bca59d9fa2095b9a0a461c34f43
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D275-03
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D275-02
filingDate 2006-04-03^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2011-02-22^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1915a54896265b5eacd2c63aaaf2c9f8
publicationDate 2011-02-22^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-7893273-B2
titleOfInvention Preparation of N-substituted isothiazolinone derivatives
abstract Provided is a process for the preparation of an N-substituted isothiazolinone derivative having the general formula (I), comprising reacting N-substituted 3-mercaptopropionamides of formula (II) or N,N′-bis-substituted 3,3′-dithiodipropionamides of formula (III) with sulfuryl chloride in the absence of solvents. Also provided is a process for the preparation of a compound having the general formula (III), comprising reacting a methyl ester of formula (IV) with an amine of formula (V) in a solvent of methanol. As no addition solvent is used in the process of the invention, the cost of manufacturing and pollution to the environment can be reduced.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012065182-A2
priorityDate 2006-04-03^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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