Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0356 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-063 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N37-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-385 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 |
filingDate |
2005-05-10^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2011-07-05^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5569ef7fdd49818b6045f22a934b5c7a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f59204a037c0bd7745291959ac48eaca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ebed5868883d6adbe61dd1bd4ac0925 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d0afc98b2549f330987af935500f551 |
publicationDate |
2011-07-05^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7972601-B2 |
titleOfInvention |
Method of promoting delivery of an antioxidant agent to a cell expression neuroligin |
abstract |
Provided are methods and compositions for treating autism spectrum disorders by administering an antioxidant or agent that stabilize or enhance expression of altered neuroligins. An aspect of the disclosure includes site-specific delivery of the antioxidant to the endoplasmic reticulum (ER) to reverse incorrect disulfide binding of the protein neuroligin. Also disclosed is a method of targeting the antioxidant to neuroligin by using the calcium binding or other recognition site of neuroligin to bind the antioxidant. The antioxidant can be cysteamine linked to a molecule which binds to a binding site. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013058871-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10039777-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012149034-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8748574-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11726099-B2 |
priorityDate |
2004-05-11^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |