http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7985880-B2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fec576c38e34882531ca37d6b922bf42 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B53-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-00 |
filingDate | 2007-06-25^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2011-07-26^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f54c83196360dd9a103e7d0b7c4d2666 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f364d26f5bb21f1e7b6e0b88cf71a1b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e53fe3f245427232b2821ab44ca675f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7516e201cee558b578dbe7e832ac8ed6 |
publicationDate | 2011-07-26^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-7985880-B2 |
titleOfInvention | Method for producing optically active 1-(fluoro-, trifluoromethyl- or trifluoromethoxy-substituted phenyl) alkylamine N-monoalkyl derivative |
abstract | There is provided a method for producing an optically active 1-(fluoro-, trifluoromethyl- or trifluoromethoxy-substituted phenyl)alkylamine N-monoalkyl derivative, which includes the steps of conducting reductive alkylation of an optically active secondary amine and a formaldehyde (including an equivalent thereof) or lower aldehyde in the presence of a transition metal catalyst under a hydrogen gas atmosphere, thereby converting the secondary amine to an optically active tertiary amine of the formula, and subjecting the tertiary amine to hydrogenolysis. The target optically active compound can be produced efficiently by this production method. |
priorityDate | 2006-06-30^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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