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publicationDate 2012-03-13^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8133692-B2
titleOfInvention Methods of predicting responsiveness to chemotherapeutic agents and selecting treatments
abstract Methods are provided for predicting responsiveness of cancer cells to chemotherapy by measuring the level of phosphorylated Stat or the level of expression of Survivin in a cancer and comparing the level in the cancer cell to the respective level in a control. Also provided are methods of selecting a chemotherapeutic treatment for a subject diagnosed with cancer by measuring the level of phosphorylated Stat or the level of expression of Survivin in a cancer and comparing the level in the cancer cell to the respective level in a control. Kits for performing the methods are also provided. Methods for modulating Survivin-dependent apoptosis in a cancer cell are also disclosed.
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID42890
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA0PJ26
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID23830
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP04665
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID85236
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID129683629
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA0MD36
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID249332
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP17881
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID396512
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226399177
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID480438
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID47757
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP16993
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID129430288
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID396341
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA3Q5F7
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP16988
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226396360
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226405416
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO02789
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP16987
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID373110
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP16986
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID3690
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA4WDW7
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226396787
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP16985
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID65070
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID114401
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID30751
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8BDE6
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP16984
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8BDE5
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID24842
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP16983
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID842674
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8BDE4

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