Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d74b7815a11e7ed5564eae0a46ce174 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff18f761530219b881918ee5bb1a821a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d22b649c54d79d7c1eabf23085b14a3e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c8e3b07b99c562e5e6bef46d3c7122ed |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10134 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16233 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6037 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5252 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-32634 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-102 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-295 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-102 |
filingDate |
2010-05-24^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-03-20^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a73569b3a93a8f641197b7338a8c4eb8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ed2e65d70f9541f320389c95f45d1f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79741cca5f5c4450063f67b958e50869 |
publicationDate |
2012-03-20^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8137681-B2 |
titleOfInvention |
Polyanionic polymer adjuvants for Haemophilus influenzae B saccharide vaccines |
abstract |
The present invention relates to the field of vaccines, and in particular vaccines comprising antigens of low isoelectric point at pH 7.0, in particular the capsular polysaccharide or oligosaccharide of H. influenzae B (PRP). Immunogenic compositions and methods of making such compositions are presented in which the PRP is surprisingly protected from immune interference by adding a polyanionic polymer (such as PLG—poly-L-glutamic acid) to the composition. |
priorityDate |
2003-06-16^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |