| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53e71b37625689520f1eb141004e3bfd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec3d7a9a543c4214ef75cdabb2d0e04b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-647
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-775
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-8125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-644
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0066 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 |
| filingDate |
2011-08-04^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-05-01^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6bd3283aaaa65e139ffe7ff33400e56 |
| publicationDate |
2012-05-01^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8168425-B2 |
| titleOfInvention |
Expression of factor IX in gene therapy vectors |
| abstract |
Two mechanisms are provided for improving the expression of Factor IX in gene therapy vectors. The first is the use of a specific Factor IX polynucleotide coding sequence designed for optimal expression. The second is the use of transcriptional regulatory regions minimized in size so that they can be used to express Factor IX, as well as any other gene of interest, in a size-constrained environment such as in a self complementary gene therapy vector system. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11517631-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10842885-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11306329-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10610606-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017180861-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11191847-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021142376-A1 |
| priorityDate |
2004-09-22^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |