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filingDate 2009-05-08^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2012-05-08^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a292021e1154aeb107f757930b0e04e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e6f7ae72ad685a0159c676ac1805b86
publicationDate 2012-05-08^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8173689-B2
titleOfInvention 6-O-substituted benzoxazole and benzothiazole compounds and methods of inhibiting CSF-1R signaling
abstract Benzoxazole and benzothiazole compounds and the stereoisomers, tautomers, solvates, oxides, esters, and prodrugs thereof and pharmaceutically acceptable salts thereof are disclosed. Compositions of the compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier, and uses of the compounds, either alone or in combination with at least one additional therapeutic agent are also disclosed. The embodiments are useful for inhibiting cellular proliferation, inhibiting the growth and/or metathesis of tumors, treating or preventing cancer, treating or preventing degenerating bone diseases such as rheumatoid arthritis, and/or inhibiting molecules such as CSF-1R.
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