| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bcb146c68b67089013b4c7a614504254
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be64ba39f81bfc0007adec2903f79385
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad45e2d3697ad8b3a494ea781443b108
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_16d27217f2815862c01d4b13a10d4cd5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_af313b4788f82055805232ade2eb0be8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9108d30c3372b82112a07c230bb2c819
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14bb12543c0ecb122de3594381c8e256
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_350f64177385856dcc9b7f29512034d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ccaa9e6a8983dae3b1f5a39b5c0a0fe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_235918ec4b167a685d3e57055863bb6e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y10-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2299-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y113-12005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y308-01005 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0069
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y30-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-26 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
2011-02-04^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-06-19^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26255e5904ba093ed3964a354fd96f21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39ea4800672c5ffdc7cad2ccc95da65f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c03185d1744eb3673af9459e464b1167
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6f6ba56256213d66f037a777485c857
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43bbf4d358571abc5c2c380bad115f20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8599e321eee5ce36193a44c6477e968
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff9f269bd8a72e8374bc6445d2e5f7d6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f2fc23f130c989ab9d235dc0398a760
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed626af47b35c86bef2da62acfeca7a8 |
| publicationDate |
2012-06-19^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8202700-B2 |
| titleOfInvention |
Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule |
| abstract |
A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate and has at least two amino acid substitutions relative to the wild-type hydrolase. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9139836-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013050204-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8669103-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9790537-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9938564-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10976312-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020212537-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8809529-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10168323-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9951373-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11453870-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11072811-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11072812-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3816180-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10774364-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9927430-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014093671-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9487520-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11661623-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9840730-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9551705-B2 |
| priorityDate |
2003-01-31^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |