| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50c5e37fee5914198ad6a28a22634853
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e44333393916a1ef9c9f10566af4833d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2619e03ba0d307debb2d4a4208128dd3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f26cc110107256642705ca01f24bbbce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4c03b04055a3d564a0a72ee9441ba019 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-605
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-635
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-605
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-635
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate |
2007-10-30^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-08-28^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26442580dd92baa6c17a714752de09e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98093a53da80e88da73fa7d071de486d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5dbeea8b20a12ccaa29f029e419690a8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84b4e8b1cfa92c2b5813a61b19660e0f |
| publicationDate |
2012-08-28^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8252580-B2 |
| titleOfInvention |
Bacterial host cell for the direct expression of peptides |
| abstract |
Expression systems are disclosed for the direct expression of peptide products into the culture media where genetically engineered host cells are grown. High yield was achieved with a special selection of hosts, and/or fermentation processes which include careful control of cell growth rate, and use of an inducer during growth phase. Special universal cloning vectors are provided for the preparation of expression vectors which include control regions having multiple promoters linked operably with coding regions encoding a signal peptide upstream from a coding region encoding the peptide of interest. Multiple transcription cassettes are also used to increase yield. The production of amidated peptides using the expression systems is also disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9833411-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9399017-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9457086-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9744140-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9526785-B2 |
| priorityDate |
2004-03-12^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |