http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8257918-B2

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-50
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-62
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filingDate 2005-07-07^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2012-09-04^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0666d3e5f350b84e7575d40e31383a6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb6bd68e4fac3b95d29586d7b72a4fad
publicationDate 2012-09-04^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8257918-B2
titleOfInvention Intelligent nanomedicine integrating diagnosis and therapy
abstract A method of controlling the activity of a biologically active compound. The method concerns an oligonucleotide-based compound, comprising a hairpin-forming oligonucleotide, an effector moiety physically associated with the oligonucleotide, where the effector moiety possesses a biological activity, and a regulating moiety physically associated with the oligonucleotide, where the regulating moiety controls the biological activity of the effector moiety by interacting with the effector moiety. The oligonucleotide can assume a hairpin configuration, where the effector and regulating moieties interact, or an open configuration, where the effector and regulating moieties fail to interact. Depending on the nature of the effector and regulating moieties, either configuration can result in the expression of the biological activity of the effector moiety.
priorityDate 2004-07-07^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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