http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8324431-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7c6bf85bdaca6452b24b74f8cdb10ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca1fb2eedc42ca63e0186e6ccb69fb7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b89465048bf6f534f53833b0bfca21c1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-46 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-00 |
| filingDate | 2008-02-16^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-12-04^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c9452ab20fc155cca262c0cf16a1af5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_137425cdf85c80a464f407caf7682049 |
| publicationDate | 2012-12-04^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8324431-B2 |
| titleOfInvention | Process for preparing 2,4-dihydroxyphenyl 4-methoxybenzyl ketones |
| abstract | The invention relates to a process for preparing 2,4-dihydroxyphenyl 4-methoxybenzyl ketones of the formula (I) by Friedel-Crafts acylation in hydrogen fluoride (HF). 2,4-Dihydroxyphenyl 4-methoxybenzyl ketones of the formula (I) in which R1 and R2 are each hydrogen, chlorine, fluorine, bromine, iodine, CF3, methyl, optionally substituted alkoxy, —OCF3, —C(CH3)3, —CH2(CH3)2, —CH(CH3)2, R3 is hydrogen, Cl, F, Br, optionally substituted alkyl, optionally substituted alkoxy, —C(CH3)3, and X is hydroxyl, F, Cl, Br, optionally substituted alkoxy, are obtained in high yield and high purity by reacting phenylacetic acid derivatives of the formula (II) with phenols of the formula (III) in liquid hydrogen fluoride (HF). |
| priorityDate | 2007-02-26^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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