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filingDate 2004-01-21^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-06-11^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f85752aaf92f7537692561dd735b113
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publicationDate 2013-06-11^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8460864-B2
titleOfInvention Methods for identifying compounds that modulate untranslated region-dependent gene expression and methods of using same
abstract The present invention relates to methods for identifying compounds that modulate untranslated region-dependent expression of a target gene. The invention particularly relates to using untranslated regions of a target gene or fragments thereof linked to a reporter gene to identify compounds that modulate untranslated region-dependent expression of a target gene. The methods of the present invention provide a simple, sensitive assay for high-throughput screening of libraries of compounds to identify pharmaceutical leads.
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