| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df7050137eda0cbd9707d78ea07d9093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44e1d9ff2fb73293200a1e0cbb0395e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d492e4065b6d619232bad813937e4a6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e41651508566f0385833e1ba14a21ffd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7be91c7aed12b7493c1df83c73b910d6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d5e58cd8ac1c8f9fcbea94e99f5c3e41 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y10-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate |
2012-09-11^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2013-09-17^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d54e5a1e7c988c86135f28e7f9d005d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d666e1c7de4101f038b41fdbc3b506f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7f9a9ba94d065d334a2ba6411e8fd86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_506cdee127d5a78ce84dac30653480e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c0ae53bf53dda087607c676b6381e69 |
| publicationDate |
2013-09-17^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8535894-B2 |
| titleOfInvention |
Antibody complexes and methods for immunolabeling |
| abstract |
Provided are labeling reagents and methods for labeling primary antibodies and for detecting a target in a sample using an immuno-labeled complex that comprises a target-binding antibody and one or more labeling reagents. The labeling reagents comprise monovalent antibody fragments or non-antibody monomeric proteins whereby the labeling proteins have affinity for a specific region of the target-binding antibody and are covalently attached to a label. Discrete subsets of labeling reagent and immune-labeled complexes are provided that facilitate the simultaneous detection of multiple targets in a sample-complexes are distinguished by i) a ratio of label to labeling reagent, or ii) a physical property of said label, or iii) a ratio of labeling reagent to said target-binding antibody, or iv) by said target-binding antibody. This is particularly useful for fluorophore labels that can be attached to labeling reagents and subsequently immuno-labeled complexes in ratios for the detection of multiple targets. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10557851-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021234729-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9739773-B1 |
| priorityDate |
2001-10-12^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |