Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df5e5b8262591a32b3bb583bbd7da739 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef2e9f5ce8630d9b282043b8d060caff http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6f731a389160b4e7875bf867a64df238 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_952691937b377c26f627e5bd696ac93b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb4aedd79e3e0a48c50745b7b985c5cd |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2799-026 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-33 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-52 |
filingDate |
2011-01-24^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2013-10-01^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92ad41da85e3e71996ff592a072f010d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e73af5b7df493336bbe4bc0662360d6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_114356bcda645973c189f690e04ead64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c311245369559151816ea6ac151b21fb |
publicationDate |
2013-10-01^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8546108-B2 |
titleOfInvention |
Methods of intracellular conversion of single-chain proteins into their di-chain form |
abstract |
The present specification discloses expression constructs comprising single-chain proteins comprising a di-chain loop region comprising an exogenous protease cleavage site and a protease that can cleave the exogenous protease cleavage site located within the di-chain loop, cell compositions comprising such expression construct, and intracellular methods of converting the single-chain protein into its di-chain form. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016319265-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013071331-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10369235-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9598683-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9340813-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9938514-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9212355-B2 |
priorityDate |
2010-01-25^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |