| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a41fa876a6d539ac1bceaa525ca1f0ca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b0c2d779ae362314c6198ca43f869a41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_83d157ae381d6337ae917848c977ec75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33367db0e086a27b2e3ec892a00075b5 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2205-103
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2017-320766
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2017-320004
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2025-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M11-006 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B17-320758 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B17-22 |
| filingDate |
2011-02-15^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2013-10-08^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35161c855b4adc00366463972e93573e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45d808fa05758ceb2a8f9d670a0e4cf7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99c9496cb70a575de8031657f351bd57 |
| publicationDate |
2013-10-08^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8551130-B2 |
| titleOfInvention |
Therapeutic agent delivery system, device and method for localized application of therapeutic substances to a biological conduit |
| abstract |
The invention provides a system, device and method for localized application of therapeutic substances within a biological conduit. One embodiment comprises a rotational atherectomy device having a flexible, elongated, rotatable, drive shaft having a lumen and with an eccentric enlarged abrading head having at least one application hole attached therethrough and in communication with a therapeutic agent delivery sheath and an operator-controlled actuator. The therapeutic substances may then spray radially outwardly from the application hole(s) on the eccentric abrading head during and/or after high-speed rotation of the head. Another embodiment comprises compartments in the abrading head that hold therapeutic agent(s) for release during high-speed rotation. In each case, the therapeutic substance(s) is delivered with radial forces resulting from high-speed orbital rotation of the eccentric abrading head, driving the therapeutic substance(s) into the conduit wall. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10595893-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11357534-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11690645-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10869689-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10987126-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10925632-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11051842-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11596437-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11497522-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10405879-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9855070-B2 |
| priorityDate |
2010-02-18^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |