| abstract |
Compounds of formula (I) modulate JNK wherein X 1 and X 2 are each simultaneously N or CH; X 3 is CH—R 2 Or N—SO 2 R, where R is lower alkyl; R 1 is aryl or heteroaryl, substituted with 0-3 lower alkyl radicals; R 2 is (II), where R 3 is H, lower acyl, or an amino acid, or a pharmaceutically acceptable salt thereof. |