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publicationDate 2014-03-18^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8674121-B2
titleOfInvention Process for the production of benzofurans
abstract A process for the production of 2-alkyl-3-aroyl-5-nitrobenzofurans by acylation of 2-(2-hydroxy-5-nitrophenyl)-1-aryl-ethanones and subsequent treatment of the esters with combinations of bases and proton acids or Lewis acids. This process can be used for the production of Dronedarone. Furthermore, novel intermediates for the manufacture of Dronedarone are provided.
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