http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8697874-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28e3113097dd6d28720572e47f2f2407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad7febc392cbc90b2fed751c2f4d03eb |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 |
| filingDate | 2009-11-30^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-04-15^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2131f0731a8855f2ca7dcd747ee55cd3 |
| publicationDate | 2014-04-15^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8697874-B2 |
| titleOfInvention | Heterocyclic compound and use thereof |
| abstract | A compound represented by formula (I) or a salt thereof, which has a potent Raf inhibitory activity. n nIn formula (I), R 1 represents an optionally substituted C 1-6 alkyl, etc.; X represents —O— or —NR 2 — (wherein R 2 represents a hydrogen atom or a C 1-6 alkyl); Y represents a group represented by formula 2 (2i or 2ii)n n n(wherein ring A represents an optionally substituted benzene ring; Z represents a group represented by (1) —NR 3 CO—W 1 —, (2) —NR 3 CO—W 1 —O—, (3) —NR 3 CO—W 1 —O—W 2 —, (4) —NR 3 CO—W 1 —S—, (5) —NR 3 CO—W 1 —NR 4 —, (6) —NR 3 COO—, (7) —NR 3 COO—W 1 —, (8) —NR 3 CO—CO—, or (9) —NR 3 CONR 4 — (wherein R 3 and R 4 each represents a hydrogen atom, etc., and W 1 and W 2 each represents an optionally substituted C 1-6 alkylene, etc.); and R 5 represents an optionally substituted five- or six-membered ring group. |
| priorityDate | 2008-12-01^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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