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publicationDate 2014-05-20^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8729241-B2
titleOfInvention Characterization of O-linked glycans
abstract The present disclosure provides methods for analyzing structure and/or composition of glycoproteins and glycans of glycoproteins. Such methods can include subjecting a glycoprotein preparation to a condition that removes at least one O-linked glycan from the glycoprotein. Such methods can include subjecting a glycoprotein preparation to a condition that releases an N-glycan from the glycoprotein, e.g., prior to subjecting the glycoprotein to a condition that releases an O-glycan from the glycoprotein.
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