| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1c0fdd9bbcbee15d88b747e39ccf6d9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_803023bbcbd1fcfd4f7ad657d38cae1a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-172
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 |
| filingDate |
2009-08-11^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-08-26^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6958b89e79b7082695213bebf60eb33d |
| publicationDate |
2014-08-26^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8815508-B2 |
| titleOfInvention |
Method of identifying disease risk factors |
| abstract |
Provided herein is a method for identifying a genetic variant that is associated with development of a condition of interest (e.g., Alzheimer's disease), and genetic variants so identified. Methods of treatment with an active agent (e.g., with a particular active agent and/or at an earlier age) is also provided, upon detecting a genetic variant described herein. In some embodiments, the genetic variant is a deletion/insertion polymorphism (DIP) of the TOMM40 gene. Kits for determining if a subject is at increased risk of developing late onset Alzheimer's disease is also provided. Kits for determining if a subject is responsive to treatment for a condition of interest with an active agent are further provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11214829-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11021751-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015073022-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015073025-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11179375-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013080182-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10865449-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9724339-B2 |
| priorityDate |
2008-08-12^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |