| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b68bb9ba976520aa80fd771645d0934d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d49d1bbee9f8d9841ae0deb6c7e644d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_af92759c928daeb7f0daabbb0499f059
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c61096aa21f5d28866a972f93ebd0306 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-485
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2005-05-30^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-12-30^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f3c85dce4c1420f9c223af8a90c72eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1703bf0a746644327ec9f8a7e2236b91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bab35cb4f6e915c973da958c38abcbf3 |
| publicationDate |
2014-12-30^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8921057-B2 |
| titleOfInvention |
Method of assessing properties of mammalian cells, and method of diagnosing cancer using the same |
| abstract |
A CDK profile including a ratio of specific activities of two cyclin dependent kinases closely correlates with the malignancy grade and the presence/absence of the sensitivity to an irritant such as an anticancer agent of a cancer tissue in clinical medicine. Therefore, the properties of a mammalian cell, such as malignancy grade, proliferation potency, sensitivity to an irritant such as an anticancer agent can be assessed based on its CDK profile or by comparing the result of a specific activity ratio of two CDKs with a predetermined threshold corresponding to the ratio. This sensitivity assessing method shows a high ratio of correct assessing results particularly in positive or sensitivity and is useful in predicting efficacy of chemotherapy using the anticancer agent. |
| priorityDate |
2004-05-31^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |