| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be64ba39f81bfc0007adec2903f79385
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_16d27217f2815862c01d4b13a10d4cd5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_235918ec4b167a685d3e57055863bb6e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14bb12543c0ecb122de3594381c8e256
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d41e61e10155deb144bb52f1d9ccbcd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_af313b4788f82055805232ade2eb0be8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bcb146c68b67089013b4c7a614504254 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-80 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y308-01005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N- |
| filingDate |
2012-04-18^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-12-30^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7cdca5d82cb6e4c701431c7e2c1afcba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4a3f07ea738ae5d69827dfdfe393963
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39fe322b81f492f74aa41b3ce2232189
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d6af1415e662435e4672221c314ce81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4eda9c6542e544aed48db0b785e2fe19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ac9a09de415a9f44d39312d66423305 |
| publicationDate |
2014-12-30^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8921620-B2 |
| titleOfInvention |
Compositions comprising a dehalogenase substrate and a contrast agent and methods of use |
| abstract |
A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11028424-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9540402-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11072811-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11072812-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10240184-B2 |
| priorityDate |
2003-01-31^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |