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filingDate 2007-01-12^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-02-03^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ff4640818265e5383185bfb476c5db9
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publicationDate 2015-02-03^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8946380-B2
titleOfInvention Liposome allowing liposome-entrapped substance to escape from endosome
abstract With the aim of providing a liposome, having a hydrophilic polymer introduced into the outer surface of the liposome membrane, which is a liposome capable of allowing the liposome-entrapped substance to escape from the endosome and be released into the cytoplasm, a liposome membrane component bound to the peptide shown by (a) or (b) below and a liposome membrane component bound to one end of a hydrophilic polymer the other end of which is bound to the peptide shown by (a) or (b) below are included in the liposome:n (a) a peptide comprising the amino acid sequence of SEQ ID NO:1; (b) a peptide comprising the amino acid sequence of SEQ ID NO:1 with 1 or more amino acids deleted, replaced or added therein, and capable of fusing lipid membranes with one another under acidic conditions.
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