| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9103a78cbea27c71dce1a67f19e79879
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b7fb2a570f47c71a94c5c3a3fd540674
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_087bed7abab91ae0f927879f9fe8b273 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6813
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 |
| filingDate |
2011-06-07^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-02-24^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf5eef54459bd98d34cd09db5ee4c230
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbf18c95980e4e1127b98b2845e25719 |
| publicationDate |
2015-02-24^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8962582-B2 |
| titleOfInvention |
PKR activation via hybridization chain reaction |
| abstract |
The present application relates to the use of hybridization chain reaction (HCR) to form double stranded RNA polymers in the presence of a target, such as a nucleic acid associated with a disease or disorder. The RNA polymers are preferably able to activate the RNA-dependent kinase PKR. Activation of PKR via RNA-HCR can be used to treat a wide variety of diseases and disorders by specifically targeting diseased cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10450599-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9217151-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11214825-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9834439-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10815519-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9856472-B2 |
| priorityDate |
2005-10-07^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |