Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9040d84b572987ece04c886efa95b31f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be91928e139e20245f1e81a49bc38667 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc2b03342511abc88f60c63f2acd96d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac4c9598b0e9037b76c11e8c7fa874ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10ab8c8a7abc6be55318e8116695daf7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a9423e5b90e365a938da3f395c810b6 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-08 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D267-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-08 |
filingDate |
2013-12-13^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2015-07-28^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4290cdcb6c8b2b92ae659b67955d7d24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_742294166f9f3348f3d75bdc124851f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78249b7e66c0a272edfadd09799a3ce7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25701cba1bd2c2fb96ff6f9dc0f636bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26eafac7628afeb4790641f986a0e2b9 |
publicationDate |
2015-07-28^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9090627-B2 |
titleOfInvention |
Batrachotoxin analogues, compositions, uses, and preparation thereof |
abstract |
Compounds relating to batrachotoxin are provided, in particular analogs that modulate the activity of sodium channels. Also provided are pharmaceutical compositions comprising compounds of the invention and a pharmaceutically acceptable carrier, including vehicles that modulate transdermal permeation of the compound. The subject compounds are useful in treatments, including treatments to reduce neuronal activity or to bring about muscular relaxation. The compounds also find use in the treatment of subjects suffering from a voltage-gated sodium channel-enhanced ailment or from pain. Further methods are provided for the preparation of the batrachotoxin-related compounds. |
priorityDate |
2012-12-14^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |