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filingDate 2012-05-04^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-09-08^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f41deae15ca7af30efba18b176a261a2
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publicationDate 2015-09-08^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-9126201-B2
titleOfInvention Methods and apparatuses for convective polymerase chain reaction (PCR)
abstract The present invention provides a method and apparatus for amplifying a nucleic acid sequence by polymerase chain reaction (PCR). The method comprises placing a PCR sample in a container which is heated by only a single heat source that provides a high temperature for denaturation in the bottom of the PCR sample, while annealing and extension automatically occur in different regions of the PCR sample due to the convection induced by a temperature gradient descending from the bottom of the PCR sample to the surface of the PCR sample.
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