http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9250230-B2

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bf5fc794065d4279d9a14acab8402eff
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5073
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
filingDate 2013-08-01^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-02-02^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8509d79de6740018944d443efbf0ed7d
publicationDate 2016-02-02^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-9250230-B2
titleOfInvention Using induced pluripotent stem cells for screening anti-neoplastic agents
abstract The invention uses induced pluripotent stem cells (iPSCs) for screening anti-neoplastic agents by examining the capability of a single agent, compound or drug, or a combination of multiple agents, compounds or drugs, for inhibiting or suppressing one or more neoplastic activities or processes, including aerobic glycolysis and neoplastic anabolism and, thus, inhibiting rapid growth and excessive reproduction of neoplastic cells. Agents, compounds or drugs may also be screened for their potential in inhibiting an invasion and/or migration of neoplastic cells into healthy or normal tissues and/or cells and a metastasis of neoplastic cells into other sites of the body. Anti-neoplastic agents, compounds and/or drugs found through these methods may represent broad-spectrum anti-neoplastic agents, compounds and/or drugs that preferentially target and damage neoplastic tumor or cancer cells but exert limited or minimal harm to normal or healthy cells.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018232079-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021150919-A1
priorityDate 2011-02-01^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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