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filingDate 2011-09-29^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-05-24^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5906b6dca13d7389f2e90194a34f91f2
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publicationDate 2016-05-24^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-9347050-B2
titleOfInvention Mannosidases capable of uncapping mannose-1-phospho-6-mannose linkages and demannosylating phosphorylated N-glycans and methods of facilitating mammalian cellular uptake of glycoproteins
abstract The invention provides mannosidases capable of uncapping mannose-1-phospho-6-mannose moieties and demannosylating phosphorylated N-glycans, methods of using such mannosidases, glycoproteins produced using the methods, as well as methods of facilitating mammalian cellular uptake of glycoproteins.
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