http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9526769-B2

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filingDate 2007-06-06^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-12-27^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_242ef8491968c973662b042740f19d38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_550327c0dad2a17cf9685286c01840ac
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publicationDate 2016-12-27^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-9526769-B2
titleOfInvention Macrocylic oximyl hepatitis C protease inhibitors
abstract The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: n nwhich inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
priorityDate 2006-06-06^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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