Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5bc5292a07e34d16eb1d033a16d3aec3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d3a63854c7a1afe23086eebce835f46 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-32 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
filingDate |
2014-08-28^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2017-01-31^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d313796ff2141e7fbd825cef18e85ab9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ba8e8065e0d7d6d0f264ef74a791687 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9dd34b85f319747e493d1c60f402e8c2 |
publicationDate |
2017-01-31^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9556170-B2 |
titleOfInvention |
Substituted-1H-benzo[d]imidazole series compounds as lysine-specific demethylase 1 (LSD1) inhibitors |
abstract |
The present invention provides compounds which are useful as inhibitors of lysine-specific demethylase 1 (“LSD1”). The present invention also relates to pharmaceutical compositions containing these compounds. The present invention also relates to a method for preparing these compounds. The present invention also relates to a method of treating a mammalian disorder in which LSD1 levels are elevated by administering these compounds and compositions to a patient in need thereof. The present invention also relates to a method for decreasing histone demethylase activity in a mammal comprising administering to the mammal an effective amount of these compounds and compositions. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019084395-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11369608-B2 |
priorityDate |
2013-08-30^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |