| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1f1f35633312a8d06bd38f8e9a88073a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2543-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2521-327
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2531-125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2521-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-307
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-161
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2537-143 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6841
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6809 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2013-08-22^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-01-31^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_954afbb72282174e8a2567960194b96c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_597a77f9d25f00139910b25f2962dd65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e1411723193de8d859759f9af8ec54b |
| publicationDate |
2017-01-31^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9556473-B2 |
| titleOfInvention |
Methods for identifying nucleic acid sequences |
| abstract |
Embodiments relate to the detection of RNA in a sample of cells. More particularly, methods concern the localized detection of RNA in situ. The method relies on the conversion of RNA to complementary DNA prior to the targeting of the cDNA with a padlock probe(s). The hybridization of the padlock probe(s) relies on the nucleotide sequence of the cDNA which is derived from the corresponding nucleotide sequence of the target RNA. Rolling circle amplification of the subsequently circularized padlock probe produces a rolling circle product which may be detected. Advantageously, this allows the RNA to be detected in situ. In additional methods, rolling circle amplification products are sequenced. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11434525-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11680288-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11788123-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11753678-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11492662-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11643679-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11331019-B2 |
| priorityDate |
2011-02-15^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |