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filingDate 2014-01-14^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-10-10^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8356a2663d5c34e7845b02fa6d62f271
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f535b73756356add204359ab2f26dc3f
publicationDate 2017-10-10^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-9783843-B2
titleOfInvention Encoded self-assembling chemical libraries (esachel)
abstract The invention provides a chemical compound comprising a chemical moiety (p) capable of performing a binding interaction with a target molecule, and an oligonucleotide (b) or functional analogue thereof. The oligonucleotide (b) or functional analogue comprises at least one self-assembly sequence (b1) capable of performing a combination reaction with at least one self-assembly sequence (b1′) of a complementary oligonucleotide or functional analogue bound to another chemical compound comprising a chemical moiety (q). In some embodiments, the chemical compound comprises a coding sequence (b1) coding for the identification of the chemical moiety (p) and further comprises at least one self-assembly moiety (m) capable of performing a combination reaction with at least one self-assembly moiety (m′) of a similar chemical compound comprising a chemical moiety (q). The invention also provides corresponding libraries of chemical compounds as well as methods of biopanning of for target molecules and of identifying such targets.
priorityDate 2002-03-08^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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