Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76fc690bdfd2fa1c7586827188eb10c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9152ce12d7b5b067b4b82944839e62e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e757fd4fedc4fe825bb81b1b466a0947 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f7f2b4e5865e08c4b8590d51cd56145 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-726 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-723 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-72 |
filingDate |
2012-12-26^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2017-10-17^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97f2adfc5aa27040bdb698e42eb4fdd6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96474a133cf72d1907cae2e90f12a419 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7175819d3cea9f3439143c56135509c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e12966b1f84890d912b3f21fb1d14c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_896b3584160aa4852397bb8d0ef5a87e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e6bd65069f4a8c6d6bcae018925c246 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_384a4d1c13d2684e51a2cf9cd57daec3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99fda58c80079aae6e00afa31deae18d |
publicationDate |
2017-10-17^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9791453-B2 |
titleOfInvention |
Methods for determining binding capability of target ligands with G protein-coupled receptors using translocation through nanochannels |
abstract |
A mechanism is provided for utilizing a nanodevice to distinguish molecules with different structure. The molecules translocate through or across a nanochannel filled with a electrolyte solution. An electrical signal through the nanochannel is measured for every translocation event. Inner surfaces of the nanochannel include a functional layer, which is a coating to functionalize the nanochannel, in which the functional layer is configured to interact with predetermined ones of the molecules during translocation events. It is determined that a combination of at least two different molecules is formed based on predetermined ones of the molecules interacting with the functional layer to change the electrical signal and/or change a translocation time for the translocation event. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11079377-B2 |
priorityDate |
2012-12-26^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |