Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_330896398ac304e0c3cb5bea4233771b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2017-00623 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2017-0065 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B17-0057 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-148 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L71-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-0031 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61D1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-00 |
filingDate |
2015-05-28^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-01-09^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01e19d42e7979e6d5498c1518a350517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8312576bc32dca0de47ef4e760e5dff |
publicationDate |
2018-01-09^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9861348-B2 |
titleOfInvention |
Chitosan and polyethylene glycol copolymers and methods and devices for using same for sealing a vascular puncture |
abstract |
A sealant is provided for sealing a puncture through tissue that comprises an elongate first section including a proximal end, a distal end, and a cross-section sized for delivery into a puncture through tissue, and a second section extending from the distal end of the first section. The first section may be formed from a freeze-dried hydrogel that expands when exposed to physiological fluid within a puncture. The first section comprises chitosan and at least one additional polymer. The second section may be formed from a solid mass of non-freeze-dried, non-cross-linked hydrogel precursors. The precursors are in an unreactive state until exposed to an aqueous physiological environment, whereupon the precursors undergo in-situ crosslinking with one another to provide an adhesive layer bonded to the first section. The second section may further comprise chitosan. Apparatus and methods for delivering the sealant into a puncture through tissue are also provided. |
priorityDate |
2014-05-29^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |