| abstract |
The present invention relates to amido-substituted azole compounds of general formula (I), in which X 1 , X 2 , R 1 , R 2 , R 4 , R 5 , R 7 and R 8 are as defined in the claims which are inhibitors of TNKS1 and/or TNKS2, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients. |