| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4a265a171804e8aca976805f97f86ddf |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-185
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-145 |
| filingDate |
2016-10-03^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2018-03-27^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb75c7a43ca8fe0d15f11ee2fa3e8d11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff6005e5f40c6a52f75949a8c2f60c6a |
| publicationDate |
2018-03-27^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9925154-B2 |
| titleOfInvention |
Cysteamine in the treatment of fibrotic disease |
| abstract |
Fibrotic diseases are characterized by the replacement of healthy tissue with scar tissue and extracellular matrix in response to tissue damage. Here we describe the reduction of extracellular matrix (ECM) deposition, interstitial fibroblasts, interstitial volume, expression of Collagen I mRNA and protein, expression of profibrotic cytokines and macrophage infiltration by Cysteamine treatment. |
| priorityDate |
2011-10-26^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |