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filingDate 2016-01-29^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-05-01^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2018-05-01^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-9957392-B2
titleOfInvention Fluorescent probe for imaging lymph nodes
abstract Disclosed is a near-infrared fluorescent imaging agent comprising an indocyanine-based fluorescent dye and a liposome. The near-infrared fluorescent imaging agent of the present invention demonstrates high fluorescence intensity and a long anchoring time in sentinel lymph nodes, thereby making it useful for detecting sentinel lymph nodes in sentinel lymph node navigation surgery. Also disclosed is an indocyanine green derivative that is particularly suitable for use in the near-infrared fluorescent imaging agent of the present invention.
priorityDate 2010-05-31^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID239806311
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID456665515
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9VG48
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID239806198
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP04635
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID4362
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID239805990

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