| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6fee0f1448c0c6e6b10d136480284e25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6cebeb6275ed1f8733e9c55f6f015d42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5bc5292a07e34d16eb1d033a16d3aec3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5564460ca4efd0026f942729cc2a5a98
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_63097e959589fe1bbcefe0c0a723788c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-44 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-44 |
| filingDate |
2000-05-20^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28094385cb1f2a6d4332d2a1e8cce6ad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6828553bcc265c25caab880e44f2bb2c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbcbafe1c5344b51b127e4102687905b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_593d925c13b359dc054e3b06b41b7f7c |
| publicationDate |
2001-12-20^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0071080-A9 |
| titleOfInvention |
Interaction of the cyclic-amp-specific phosphodiesterase pde4d5 with rack1 |
| abstract |
It has been discovered that the cAMP-specific phosphodiesterase, PDE4D5, interacts specifically and with high affinity with the Receptor for Activated C-Kinase (RACK1). The region of PDE4D5 that interacts with RACK1 was determined, and it was shown that peptides spanning this region inhibit the specific interaction of PDE4D5 and RACK1. Drugs that inhibit or stimulate this interaction should be therapeutically important for treating various conditions. A method for screening candidate drugs involves detecting inhibition or stimulation of this interaction of the peptide and RACK1. Peptides that modulate this interaction and methods of making thereof are also disclosed. |
| priorityDate |
1999-05-20^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |