abstract |
A method for purifying muscle stem cells from a myoblast sample isolated from mammalian skeletal muscle is disclosed. Purified muscle stem cells can be used for a variety of purposes, including for systemic delivery of muscle proteins and other desired nucleic acid products to a mammal, for gene therapy, in the treatment muscle diseases, including muscular dystrophies, in the treatment or prophylaxis of inherited or acquired diseases, including genetic diseases and cancer, and in transplanting bone marrow to a mammal. |