http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02058736-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7bfd85d33ceb020006b78b3c293bc0ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_db06646fe3b73a0c42e35e8e66485973 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-522 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-522 |
| filingDate | 2001-12-12^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00fb89eace420b59d6f5c88875286eda |
| publicationDate | 2003-08-07^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-02058736-A3 |
| titleOfInvention | Use of 9-substituted purine analogues and other molecules to stimulate neurogenesis |
| abstract | The present invention is directed to a method of inducing neurogenesis by administering to a mammal an effective quantity of a compound that induces neurogenesis, where neurogenesis includes proliferation of neural stem and progenito cells, differentiation of these cells into neurons, and/or survival of these new neurons. In general, the compound comprises three moieties, A, L, and B, covalently linked. A can be a purine, tetrahydroindoone, or pyrimidine; L is a linker, while B is a moiety that promotes absorption of the compound. A particularly preferred compound is N-4-[[3-(6-oxo-1,6-diyhdropurin-9-yl)-1-oxopropyl]amino]benzoic acid (also known as AIT-082 or leteprinim potassium). Another aspect of the inventio is pharmaceutical compositions for indicing neurogenesis. |
| priorityDate | 2000-12-12^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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