abstract |
Described herein are compounds that are useful as protein kinase inhibitors, especially inhibitors of ERK, having the formula (I) wherein Ht is an optionally substituted heteroaryl ring selected from pyrrol-3-yl, pyrazol-3-yl, [1,2,3]triazol-4-yl, or tetrazol-5-yl, and A-B is N-O or O-N. The compounds are useful for treating diseases in mammals that are alleviated by a protein kinase inhibitor, particularly diseases such as cancer, inflammatory disorders, restenosis, and cardiovascular disease. |