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publicationDate 2002-03-21^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-0222610-A1
titleOfInvention Isoxazoles and their use as inhibitors of erk
abstract Described herein are compounds that are useful as protein kinase inhibitors, especially inhibitors of ERK, having the formula (I) wherein Ht is an optionally substituted heteroaryl ring selected from pyrrol-3-yl, pyrazol-3-yl, [1,2,3]triazol-4-yl, or tetrazol-5-yl, and A-B is N-O or O-N. The compounds are useful for treating diseases in mammals that are alleviated by a protein kinase inhibitor, particularly diseases such as cancer, inflammatory disorders, restenosis, and cardiovascular disease.
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