| abstract |
An optically active cis-piperidine derivative having high optical and chemical purities can be efficiently produced by optical resolution of a racemic cis-piperidine derivative (which is a cis-piperidine derivative mixture) with an optically active tartaric acid derivative or an optically active amino acid derivative. Preferable examples of the optically active tartaric acid derivative include optically active di(p- toluoyl)tartaric acid, optically active di(4-methoxybenzoly) tartaric acid, and so on, while those of the optically active amino acid derivative include optically active N-benzene- sulfonylphenylalanine and so on. |