| abstract |
The invention relates to novel polynucleotides associated with human disease, and in particular to osteoarthritis. The invention further relates to polymorphic polynucleotides associated with osteoarthritis. The invention provides methods of determining if a particular polymorphism predisposes an individual to or is associated with the development of osteoarthritis. The invention also provides methods of detecting the presence of one or more polymorphism as an indicator of osteoarthritis, and provides for use of novel polynucleotides of the invention in the development of drugs and in disease treatment. |