| abstract |
Disclosed is a method of stimulating bone growth at a site in a subject in need of osteoinduction or cartilage repair. The method comprises the step of administering a therapeutically effective amount of an agonist of the non-proteolytically activated thrombin receptor to the site. Also disclosed is a method of stimulating the proliferation and expansion of chrondroxytes in vitro. The method comprises culturing chrondrocytes in the presence of a stimulating amount of an NPAR agonist. |